Times Live Blog: Promising results in blocking HIV during first days of infection: M2010
March 2008
Up one levelQ&A: Science and Ethics can be served in Clinical Trials
By Bachi Karkaria (Times of India) 6 March 2008: Zeda Rosenberg, founder-president of the International Partnership for Microbicides (IPM), spoke to Bachi Karkaria of the hope that can be wrested from the persistent failures of clinical trials:
HIV Prevention Trials 'Hindered By Obstacles'
By T. V. Padma (SciDev.Net - New Delhi) 5 March 2008: Developing countries face several challenges to conducting clinical trials on HIV prevention strategies, scientists have cautioned.
Microbicides 2008: Third-generation microbicides might act as ‘bacterial vaccine’
By Gus Cairns (Aidsmap news - London) 4 March 2008: Studies are underway of genetically engineering naturally-occurring vaginal bacteria to produce microbicides against HIV, and in one case such a strategy has already proved effective in preventing HIV infection in monkeys, the Microbicides 2008 Conference heard last week in Delhi.
Microbicides 2008: Will adherence issues affect all the first-generation trials?
By Gus Cairns (Aidsmap news) 3 March 2008: There are still two ongoing trials of the ‘first generation’ non-ARV-based microbicide candidates ongoing, and at the Microbicides 2008 Conference last week Sharon Hillier, Principal Investigator of the Microbicides Trial Network (MTN) gave delegates an update of data from these studies.
Microbicides 2008: Cellulose sulphate has unexpected tissue toxicity
By Gus Cairns (Aidsmap news) 3 March 2008: Investigations into the candidate microbicide cellulose sulphate (Ushercell) using the substance on vaginal tissue samples have revealed that it causes loss of tissue integrity by destroying proteins that bind cells together. This allows HIV to leak into the underlying tissues.
Microbicides 2008: Microbicides might benefit men more than women
By Gus Cairns, (Aidsmap news) 1 March 2008: An antiretroviral-containing microbicide could have some very paradoxical effects, according to epidemiologist Sally Blower, speaking at the Microbicides 2008 conference last week in Delhi.