Is microbicide research on teen girls OK?
(hivplusmag.com) 30 January 2009: Young women under age 18 have high rates of HIV acquisition and thus represent an important population for the clinical research of microbicides. Microbicide trials, however, primarily enroll adult participants.
http://www.hivplusmag.com/NewsStory.asp?id=19838&sd=01/30/2009-02/01/2009
In the study "Sexuality, HIV Risk, and Potential Acceptability of
Involving Adolescent Girls in Microbicide Research in Kisumu, Kenya"
[Sexual Health, Volume 5, Number 4] the authors "sought to understand
the individual, family, and community-level factors that may influence
the acceptability of microbicide use and research involving adolescent
girls."
In Kisumu the researchers conducted 30 interviews with girls ages 14 to
17 as well as nine focus groups with adolescent girls, their parents,
and community leaders. Discussion topics included adolescent sexuality,
HIV prevention methods, perceptions about the use of microbicides, and
views about microbicide research involving adolescent girls.
The results found that while adolescent sexuality is stigmatized, it is
also "acknowledged to be a natural part of the 'adolescent stage.'
Desperation to stop the spread of HIV among youth and support for
female-initiated HIV prevention methods led to enthusiasm about
microbicides and future microbicide research."
However, participants raised numerous concerns about microbicides,
including the difficulty of using such a product in a timely fashion
"due to the rushed, unplanned nature of adolescent sex"; the fear of
experimental products; concerns about product efficacy; and parents'
worries that "supporting microbicide use in youth would defy societal
pressures that denounce adolescent sexual activity."
"Microbicide acceptability for youth in sub-Saharan Africa may be
bolstered by desperation for new methods to stop the spread of HIV yet
hindered by misgivings about experimental HIV prevention methods for
youth," the authors concluded. "Understanding and addressing the
microbicide's perceived benefits and shortcomings -- as well as the
broader context of adolescent sexuality and HIV prevention -- may
facilitate future research and promotion of microbicides in this
high-risk group."

